Medical / Clinical / Scientific - Bioanalytical Analyst
Company: HonorVet Technologies
Posted on: March 20, 2023
Job Description: POSITION SUMMARY:
As part of the Analytical Research and Development (ARD) group in Biotherapeutics Pharmaceutical Sciences, we are seeking an enthusiastic, self-driven, and optimistic a B.S., M.S., or Ph.D. degree (with at least 7+, 5+, and 0-3 years of work experience, respectively) level candidate specializing in the mass spectrometry (MS). The successful candidate will provide support for LC-MS and LC-MS/MS method development and qualification in support of quantitation of mRNA expressed proteins in cells as well as in-depth structural elucidation of these proteins. As such, candidate should have in-depth understanding and hands-on experience with the characterization of antibodies, proteins, and/or vaccine products that includes commensurate technical knowledge and skills. Candidates should be comfortable working at the interface of analytical chemistry, biochemistry, cell biology, as well as interacting with cross-site research groups. Excellent written and communication skills, effective time-management, an innovative spirit, and the ability and desire to work both independently and collaboratively in a multidisciplinary, fast-paced, team-oriented environment are essential for the position.
" Develop, qualify, and benchmark the LC-MS and/or LC-MS/MS quantitative method to monitor expression of proteins in cells post mRNA transfection.
" Develop Client strategies and methods with the latest UHPLC and MS technologies for more informative and efficient product characterization and process monitoring.
EDUCATION AND EXPERIENCE:
" Candidates should have a B.S., M.S., or Ph.D. degree (with at least 7+, 5+, and 2-3 years of work experience, respectively) in chemistry, biochemistry or related field, and a primary focus on protein mass spectrometry, commensurate with graduate studies, postdoctoral research, and/or work experience.
TECHNICAL SKILLS REQUIREMENTS:
" Specialization in protein mass spectrometry (LC/MS, LC/MS/MS) is required. Experience with state-of-the-art MS and proficiency in data analysis is expected.
" Extensive hands-on experience with qualitative and quantitative protein analysis is required.
" Extensive experience with well-established MS approaches and methods for the detailed structural analysis of therapeutic proteins is required.
" Familiarity with mRNA/DNA and protein therapeutics is highly desired with respect to structural characterization approaches, challenges and gaps, and regulatory principles.
" MS-based method development experience is highly desired for implementing more informative and efficient approaches to product characterization and process monitoring
PHYSICAL POSITION REQUIREMENTS:
" Position requires typical physical conditions for standard laboratory and office work
" Ability to perform mathematical calculations and ability to perform complex data analysis.
1. Ph.D. preferred,
2. Advanced technology - Mass Spectrometry (Data Processing)
3. Hit the ground Running
4. mRNA Project, protein expression
3. Fast learner
4. Team Player (Collaborate with multiple teams)
5. Cell Culture Experience
6. Protein Purification, immunoprecipitation
Training Process: 2-wks
Will shadow at first.
Onsite 4-5 days
" Phone Screen
" Panel Interview via Teams
" Possible Onsite Interviews as well
Position Comments visible to MSP and Supplier: 100% Onsite Chesterfield - MO (will need to adhere to return to site policy)
Duration: 3 yrs
Job Description: POSITION SUMMARY:
Keywords: HonorVet Technologies, Chesterfield , Medical / Clinical / Scientific - Bioanalytical Analyst, Healthcare , Chesterfield, Missouri
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